ChemicalBook > CAS DataBase List > ML298
ML298
- Product Name
- ML298
- CAS No.
- 1426916-02-0
- Chemical Name
- ML298
- Synonyms
- ML298;CID53393915;ML298 >=98% (HPLC);ML-298,Inhibitor,ML 298,Phospholipase,inhibit;3,4-difluoro-N-[2-[1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]dec-8-yl]ethyl]-benzamide;Benzamide, 3,4-difluoro-N-[2-[1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]dec-8-yl]ethyl]-
- CBNumber
- CB34199383
- Molecular Formula
- C22H23F3N4O2
- Formula Weight
- 432.44
- MOL File
- 1426916-02-0.mol
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ML298 Property
- storage temp.
- 2-8°C
- solubility
- DMF: 10 mg/ml; DMSO: 20 mg/ml; Ethanol: 1 mg/ml
- form
- powder
- color
- white to beige
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Safety
- WGK Germany
- 3
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- SML1077
- Product name
- ML298
- Purity
- ≥98% (HPLC)
- Packaging
- 5MG
- Price
- $117
- Updated
- 2023/06/20
Sigma-Aldrich
- Product number
- SML1077
- Product name
- ML298
- Purity
- ≥98% (HPLC)
- Packaging
- 25MG
- Price
- $371
- Updated
- 2023/06/20
Cayman Chemical
- Product number
- 15349
- Product name
- ML-298
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $40
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 15349
- Product name
- ML-298
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $109
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 15349
- Product name
- ML-298
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $195
- Updated
- 2024/03/01
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ML298 Chemical Properties,Usage,Production
Description
ML-298 is an inhibitor of phospholipase D2 (PLD2; IC50 = 355 nM). It is selective for PLD2 over PLD1 (IC50 = 20,000 nM). It decreases invasive migration of U87-MG glioblastoma cells when used at a concentration of 10 μM without inducing cytotoxicity.
Uses
ML298 is a potent, specific inhibitor of Phospholipase D2 (PLD2).
Biochem/physiol Actions
ML298 is a potent, specific inhibitor of Phospholipase D2 (PLD2; IC50 = 355 nM). ML298 does not affect PLD1 activity at concentrations up to 20 μM.
ML298 Preparation Products And Raw materials
Raw materials
Preparation Products
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